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. 2014 May 8;8(1):291–301. doi: 10.3892/etm.2014.1704

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Counted numbers of macroscopic metastases in the lung on day 35 following tumor cell inoculation as a function of the dose of neutron beam irradiation (A) without and (B) with bevacizumab treatment following the administration of a ¹⁰B-carrier in combination with nicotinamide treatment or mild temperature hyperthermia (MTH) on day 18 following tumor cell inoculation. Circle, square, and triangle symbols represent irradiation without nicotinamide or MTH, with nicotinamide, and with MTH, respectively. Bars represent standard errors (n=9). ¹⁰B (−), no ¹⁰B-carrier; BPA, L-para-boronophenylalanine-¹⁰B; BSH, sodium mercaptoundecahydrododecaborate-¹⁰B; MTH, mild temperature hyperthermia.