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. 2014 May 8;8(1):291–301. doi: 10.3892/etm.2014.1704

Table IV.

Enhancement ratiosa due to combined treatment with bevacizumab.

Variable Without nicotinamide or MTH With nicotinamide With MTH
Surviving fraction = 0.3
 Total cell population
  Without 10B-carrier 1.25±0.1 1.05±0.1 1.3±0.1
  With BPA 1.55±0.2 1.05±0.1 1.7±0.15
  With BSH 1.35±0.1 1.05±0.15 1.35±0.15
Net micronucleus frequency = 0.3
 Total cell population
  Without 10B-carrier 1.1±0.1 1.05±0.1 1.2±0.1
  With BPA 1.2±0.2 1.05±0.1 1.3±0.15
  With BSH 1.15±0.1 1.05±0.1 1.25±0.15
 Quiesent cell population
  Without 10B-carrier 1.05±0.1 1.05±0.1 1.05±0.1
  With BPA 1.05±0.2 1.05±0.1 1.1±0.1
  With BSH 1.1±0.1 1.05±0.1 1.2±0.1

Data are presented as mean ± standard error (n=9).

a

Ratio of the dose of radiation necessary to obtain each end-point without bevacizumab to that needed to obtain each end-point with bevacizumab;

MTH, mild temperature hyperthermia; BPA, L-para-boronophenylalanine-10B; BSH, sodium mercaptoundecahydrododecaborate-10B.