Table I.
Severity and the kindling rate of rats in each treatment group.
| Seizure grade | |||||
|---|---|---|---|---|---|
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| Group | Sample (n) | Survival rate | Moderate (≤III) | Severe (≥III) | Kindling rate |
| Normal control (A) | 10 | - | - | - | - |
| Model control (B) | 10 | 10/10 | 5/10 | 5/10 | 10/10 |
| Agmatine 20 mg/kg (C1) | 10 | 10/10 | 6/10 | 4/10 | 10/10 |
| Agmatine 40 mg/kg (C2) | 10 | 10/10 | 6/10 | 4/10 | 10/10 |
| Agmatine 80 mg/kg (C3) | 10 | 10/10 | 7/10 | 3/10 | 8/10 |
The rate of severe grade seizures in agmatine groups was markedly decreased compared with the model control group, whilst no significant difference was observed between the kindling rates among the groups.