Table 2.

Significant main effects of condition (reappraise sad vs. view sad) and condition × timepoint interaction effects.

Region of activation	Direction of effects	BA	x	y	z	Z-score	Cluster (3 mm3)
Whole brain analysis
Main effect of condition (reappraise vs. view sad)
L inferior frontal gyrus	Reappraise sad > view sad	47	−35	25	−17	3.87	17
L inferior frontal gyrus	Reappraise sad > view sad	47	−45	25	−10	3.73	14
L middle temporal gyrusa	Reappraise sad > view sad	21	−51	−33	−4	3.73	53
L inferior occipital gyrus	Reappraise sad > view sad	17	−16	−92	−5	4.27	175
R cuneus	Reappraise sad > view sad	17	20	−93	−1	4.38	88
Condition (reappraise vs. view sad) × timepoint (frames 5–8) interaction effects
L inferior frontal gyrus	Reappraise sad > view sad	45	46	24	10	4.02	18
L precentral gyrusc	Reappraise sad > view sad	44	−55	12	5	4.19	32
L precentral gyrus	Reappraise sad > view sad	6	−42	−8	50	4.44	156
L medial frontal gyrusb	Reappraise sad > view sad	6	−6	4	59	4.55	114
L middle temporal gyrus	Reappraise sad > view sad	39	−46	−60	25	3.81	51
L supramarginal gyrus	Reappraise sad > view sad	40	−58	−51	26	4.22	38
L precuneus	Reappraise sad > view sad	31	−5	−60	23	3.51	13
L lingual gyrus	Reappraise sad > view sad	18	−3	−94	−6	4.57	357
R declive	Reappraise sad > view sad	*	34	−71	−21	3.94	24
R culmen	Reappraise sad > view sad	*	38	−57	−24	4.21	23
Amygdala ROI analysis
Main effect of condition (reappraise vs. view sad)
R centromedial amygdala	View sad > reappraise sad	*	25	−11	−4	3.22	9

BA, Brodmann area; Z-score for peak voxel in each ROI; cluster, number of 3 mm isotropic voxels in each ROI. Superscripts a, b, & c indicate that these effects are plotted in Fig. 4.