Table 3.
Multivariable Logistic Regression Results Predicting Early Nonadherence to Antihypertensives
| Class | Early Nonpersistence to Antihypertensives, % | Odds Ratios (95% CI) |
|---|---|---|
| Race | ||
| White | 30.6 | Referent |
| Black | 42.5 | 1.58 (1.45–1.72)a |
| Asian | 38.1 | 1.38 (1.27–1.49)b |
| Hispanic | 41.1 | 1.47 (1.37–1.59)a |
| Other/mixed/unknown | 11.3 | 1.06 (1.01–1.12)a |
| Age, y | ||
| <50 | 39.1 | |
| 50–64 | 28.7 | 0.67 (0.64–0.70)a |
| 65–74 | 28.1 | 0.66 (0.61–0.71)a |
| 75+ | 31.1 | 0.76 (0.68–0.85) |
| Sex | ||
| Male | 33.1 | |
| Female | 32.8 | 0.92 (0.88–0.96)a |
| Current smoker | ||
| No | 32.3 | Referent |
| Yes | 38.8 | 1.16 (1.09–1.24)a |
| BMI | ||
| <24.99 (normal) | 37.3 | Referent |
| 25–29.99 (overweight) | 35.7 | 0.90 (0.84–0.97)a |
| ≥30 (obese) | 36.2 | 0.84 (0.79–0.90) |
| Missing | 24.8 | 0.63 (0.58–0.69)a |
| Baseline SBP, mm Hg | ||
| <140 | 33.5 | |
| 140–149 | 36.4 | 1.07 (1.02–1.13)a |
| 150–159 | 33.3 | 0.96 (0.90–1.02)b |
| 160+ | 32.2 | 0.99 (0.93–1.06) |
| Household income, $ | ||
| <40,000 | 35.9 | Referent |
| 40,000–74,999 | 33 | 0.90 (0.85–0.95) |
| ≥75,000 | 30.9 | 0.86 (0.80–0.91)b |
| Missing | 32.1 | 1.10 (0.79–1.52) |
| Drug copay, $ | ||
| <6 | 32.9 | Referent |
| 6–10 | 33.9 | 1.06 (1.01–1.11)a |
| 11+ | 29.1 | 0.96 (0.88–1.04) |
| Comorbid conditions | ||
| Diabetes | 37.9 | 1.09 (1.00–1.18)b |
| CKD | 33.6 | 1.02 (0.88–1.19) |
| Prior CVD | 31.8 | 0.91 (0.79–1.06) |
| Concurrent depression | 38.4 | 1.08 (0.96–1.21) |
| Ever schizophrenia | 32.4 | 0.77 (0.53–1.11) |
| Ever bipolar disorder | 38.1 | 1.03 (0.81–1.32) |
| Ever anxiety | 38.9 | 1.09 (1.00–1.19) |
| Total outpatient visits | ||
| 0 | 27.7 | Referent |
| 1 or 2 | 34.6 | 1.03 (0.97–1.10)a |
| 3 to 5 | 36.3 | 1.09 (1.02–1.18) |
| 6 to 15 | 40.9 | 1.30 (1.19–1.43)a |
Abbreviations: CI, confidence interval; CKD, chronic kidney disease; CVD, cardiovascular disease; SBP, systolic blood pressure. a P≤.01. b P≤.05.