Table 3.

Multivariable analysis of maternal and fetal outcomes in subjects with history of one or multiple IABs.

Outcome	Primigravid (N=7681)	One IAB (N=642)	Two or More IABs (N=175)
Spontaneous preterm birth*	438 (5.8)	52 (8.2) 1.4 [1.0–1.9]	16 (9.3) 1.6 [1.0–2.8]
Indicated preterm birth*	231 (3.0)	22 (3.5) 1.1 [0.7–1.7]	5 (2.9) 0.9 [0.3–2.1]
Preterm PROM	172 (2.3)	31 (4.9) 2.0 [1.4–3.0]	8 (4.7) 1.8 [0.9–3.8]
Pre-eclampsia	539 (7.0)	41 (6.4) 0.9 [0.7–1.3]	13 (7.4) 1.1 [0.6–1.9]
Fetal/Neonatal death	157 (2.1)	17 (2.7) 1.2 [0.7–2.0]	7 (4.0) 1.7 [0.8–3.8]
Birthweight < 5th percentile	371 (4.9)	22 (3.5) 0.7 [0.5–1.1]	2 (1.2) 0.2 [0.1–1.0]
Neonatal intensive care admission	861 (11.2)	79 (12.3) 1.1 [0.8–1.4]	22 (12.6) 1.1 [0.7–1.7]

Data shown are number of outcomes (percent)

Odds ratio compared to the primigravid group [95% confidence interval] were calculated after adjusting for maternal age, race, education, smoking, marital status, BMI at enrollment, and study drug (placebo or vitamin C and E). Odds ratio in bold typeface are statistically significant.

IAB=induced abortion, PROM=premature rupture of membranes

^*Excludes 97 women whose current pregnancy resulted in SAB or IAB (87 primigravid, 7 one IAB, 3 two or more IABs).