Table 4.
Greatest absolute increase in exposure between 2005 and 2010
| Rank | Medication | Exposure increase* | Exposure in 2005* | Exposure in 2010* |
|---|---|---|---|---|
| 1 | Poractant alpha | 32 | 32 | 63 |
| 2 | Vitamin A | 13 | 8.3 | 21 |
| 3 | Ibuprofen | 9.1 | 1.4 | 11 |
| 4 | Fluconazole | 6.4 | 14 | 21 |
| 5 | Piperacillin/tazobactam | 6.0 | 6.2 | 12 |
| 6 | Lansoprazole | 5.7 | 9.8 | 16 |
| 7 | Methadone | 4.9 | 3.1 | 8.0 |
| 8 | Morphine | 4.8 | 49 | 54 |
| 9 | Meropenem | 4.5 | 4.5 | 9.0 |
| 10 | Nitric oxide | 3.7 | 8.9 | 13 |
| 11 | Milrinone | 3.6 | 0.4 | 4.0 |
| 12 | Cefepime | 3.2 | 4.6 | 7.8 |
| 13 | Lorazepam | 3.0 | 23 | 26 |
| 14 | Azithromycin | 2.9 | 0.1 | 3.0 |
| 15 | Metronidazole | 2.9 | 8.4 | 11 |
| 16 | Famotidine | 2.8 | 4.7 | 7.5 |
| 17 | Acyclovir | 2.4 | 16 | 18 |
| 18 | Cefazolin | 2.4 | 6.3 | 8.7 |
| 19 | Sildenafil | 2.1 | 0.2 | 2.3 |
| 20 | Linezolid | 2.0 | 0.4 | 2.4 |
*
Per 1000 infants.