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. 2014 Jun 9;5:3979. doi: 10.1038/ncomms4979

Table 1. Association of protein-coding genes, can-lncRNAs and eRNAs with NFκB binding.

Gene set Observed Expected Fold Enrichment P -value Q -value
Protein coding 188,011 66,434.98 2.83 1 × 10−4 1.6 × 10−4
can-lncRNA 11,482 2,764.43 4.15 1 × 10−4 8 × 10−4
eRNA 7,090 5,076.86 1.40 0.16 0.21
can-lncRNA (gene body) 42,150 6,854.14 6.15 1 × 10−4 3.4 × 10−4
eRNA (gene body) 39,645 6,260.16 6.33 1 × 10−4 3.4 × 10−4

Empirical P-values for associations of the respective gene sets with NF-κB binding intervals were calculated using 10,000 randomizations in a simulation procedure implemented using the Genomic Association Tester (GAT). GAT derived Q-values, used to control for the number of gene sets analysed, are also provided.