Fig. 1.

HML subset of ER⁺ breast tumors is associated with poor clinical outcome. a Index plot. Median and mean SMLs of each population are indicated with red lines. b–e Kaplan–Meier survival curves of all breast tumors (b) and the HML (red) and LML (blue) subsets of: c ER⁺ breast cancer; d ER⁻ breast cancer; and e a comparison between ER⁺ HML, ER⁺ LML, and ER⁻ (black) breast cancer. The log-rank test was used to determine p-values