Table 2.

Maternal serum organochlorine concentrations in relation to odds of gestational hypertension and preeclampsia: Collaborative Perinatal Project, 1959–1966

		Gestational hypertension				Preeclampsia
Organochlorine	Quintile	N^a	Crude OR	Adj OR^b	95% CI	N^a	Crude OR	Adj OR^b	95% CI
p, p’ – DDE	1	76	1.0	1.0		25	1.0	1.0
	2	84	1.1	1.0	0.7 – 1.6	23	1.2	1.2	0.5 –2.6
	3	63	0.8	0.7	0.4 – 1.1	27	0.9	0.8	0.3 – 1.7
	4	71	0.8	0.8	0.5 – 1.3	29	0.9	0.7	0.3 – 1.7
	5	70	1.0	0.9	0.6 – 1.5	27	1.2	0.8	0.4 – 1.8
				P for trend = 0.78				P for trend = 0.50
p, p’ – DDT	1	70	1.0	1.0		22	1.0	1.0
	2	86	1.2	1.0	0.6 – 1.6	25	1.4	1.1	0.5 – 2.5
	3	64	0.8	0.5	0.3 – 0.9	29	1.3	0.6	0.3 – 1.5
	4	85	1.3	0.8	0.5 – 1.3	20	1.0	0.4	0.2 – 1.1
	5	59	0.7	0.4	0.2 – 0.7	35	1.6	0.6	0.2 – 1.5
				P for trend = 0.002				P for trend = 0.23
Total PCBs with possibly imputed congeners	1	60	1.0	1.0		22	1.0	1.0
	2	72	1.1	1.1	0.6 – 1.8	29	1.0	0.7	0.4 – 1.5
	3	69	1.3	1.0	0.6 – 1.7	26	1.1	0.8	0.4 – 1.7
	4	69	1.2	0.9	0.5 – 1.5	29	1.0	0.6	0.2 – 1.5
	5	94	1.7	1.3	0.8 – 2.2	25	0.8	0.5	0.2 – 1.3
				P for trend = 0.39				P for trend = 0.19
B-Hexacholorocyclohexane	1	77	1.0	1.0		26	1.0	1.0
	2	93	1.0	0.8	0.5 – 1.3	22	0.8	0.7	0.3 – 1.7
	3	69	0.7	0.6	0.4 – 0.9	19	0.7	0.8	0.4 – 1.9
	4	66	0.7	0.5	0.3 – 0.8	23	0.6	0.5	0.2 – 1.3
	5	57	0.6	0.5	0.3 – 0.8	38	1.4	1.2	0.5 – 3.2
				P for trend = 0.01				P for trend = 0.41
Dieldrin	1	45	1.0	1.0		21	1.0	1.0
	2	67	1.4	1.4	0.8 – 2.3	24	1.1	0.9	0.4 – 2.1
	3	85	1.9	1.9	1.1 – 3.2	18	0.8	0.7	0.3 – 1.7
	4	82	1.7	1.8	1.0 – 3.0	30	1.0	0.7	0.3 – 1.7
	5	74	1.8	1.7	1.0 – 3.0	35	1.6	1.0	0.4 – 2.2
				P for trend = 0.12				P for trend = 0.95
Heptachlor Epoxide	1	64	1.0	1.0		31	1.0	1.0
	2	58	0.6	0.5	0.3 – 0.9	23	1.0	0.7	0.3 – 1.5
	3	75	0.9	0.7	0.4 – 1.1	20	0.8	0.6	0.2 – 1.4
	4	83	1.1	0.7	0.4 – 1.3	24	1.1	0.7	0.3 – 1.8
	5	72	1.0	0.5	0.3 – 1.0	28	0.9	0.9	0.3 – 3.0
				P for trend = 0.11				P for trend = 0.98
Hexachlorobenzene	1+2	140	1.0	1.0		58	1.0	1.0
	3	70	1.0	1.0	0.7 – 1.6	28	0.8	0.9	0.5 – 1.8
	4	85	0.9	0.8	0.5 – 1.3	17	0.4	0.3	0.1 – 0.6
	5	62	0.9	1.0	0.6 – 1.6	25	0.5	0.4	0.2 – 0.9
				P for trend = 0.72				P for trend = 0.01
trans-Nonachlor	1+2	144	1.0	1.0		40	1.0	1.0
	3	69	1.1	0.9	0.6 –1.4	33	1.3	1.1	0.5 –2.3
	4	71	0.9	0.8	0.5 – 1.3	28	0.9	0.6	0.3 – 1.4
	5	78	1.0	0.9	0.5 – 1.4	30	1.5	0.8	0.3 – 1.8
				P for trend = 0.51				P for trend = 0.47
Oxychlordane	1+2	124	1.0	1.0		45	1.0	1.0
	2	71	1.0	0.8	0.5 – 1.2	23	0.9	0.7	0.3 – 1.6
	3	70	1.2	1.0	0.6 – 1.5	27	1.0	0.8	0.4 – 1.8
	4	78	1.2	0.9	0.6 – 1.6	24	0.9	1.0	0.4 – 2.5
				P for trend = 0.93				P for trend = 0.96

Number after restrictions for adjusted analyses

Adjusted for age groups (3 indicators), center (11 indicators), triglycerides (continuous), cholesterol (continuous), prepregnancy BMI (continuous), previous pregnancy with IPI < 2years (nullips in reference group), previous pregnancy with IPI >= 2 years, race (two indicator variables), SES (continuous), maternal age (2 indicators) and smoking status (4 indicators).