Table 2.
Gestational hypertension | Preeclampsia | ||||||||
---|---|---|---|---|---|---|---|---|---|
Organochlorine | Quintile | Na | Crude OR |
Adj ORb | 95% CI | Na | Crude OR |
Adj ORb | 95% CI |
p, p’ – DDE | 1 | 76 | 1.0 | 1.0 | 25 | 1.0 | 1.0 | ||
2 | 84 | 1.1 | 1.0 | 0.7 – 1.6 | 23 | 1.2 | 1.2 | 0.5 –2.6 | |
3 | 63 | 0.8 | 0.7 | 0.4 – 1.1 | 27 | 0.9 | 0.8 | 0.3 – 1.7 | |
4 | 71 | 0.8 | 0.8 | 0.5 – 1.3 | 29 | 0.9 | 0.7 | 0.3 – 1.7 | |
5 | 70 | 1.0 | 0.9 | 0.6 – 1.5 | 27 | 1.2 | 0.8 | 0.4 – 1.8 | |
P for trend = 0.78 | P for trend = 0.50 | ||||||||
p, p’ – DDT | 1 | 70 | 1.0 | 1.0 | 22 | 1.0 | 1.0 | ||
2 | 86 | 1.2 | 1.0 | 0.6 – 1.6 | 25 | 1.4 | 1.1 | 0.5 – 2.5 | |
3 | 64 | 0.8 | 0.5 | 0.3 – 0.9 | 29 | 1.3 | 0.6 | 0.3 – 1.5 | |
4 | 85 | 1.3 | 0.8 | 0.5 – 1.3 | 20 | 1.0 | 0.4 | 0.2 – 1.1 | |
5 | 59 | 0.7 | 0.4 | 0.2 – 0.7 | 35 | 1.6 | 0.6 | 0.2 – 1.5 | |
P for trend = 0.002 | P for trend = 0.23 | ||||||||
Total PCBs with possibly imputed congeners | 1 | 60 | 1.0 | 1.0 | 22 | 1.0 | 1.0 | ||
2 | 72 | 1.1 | 1.1 | 0.6 – 1.8 | 29 | 1.0 | 0.7 | 0.4 – 1.5 | |
3 | 69 | 1.3 | 1.0 | 0.6 – 1.7 | 26 | 1.1 | 0.8 | 0.4 – 1.7 | |
4 | 69 | 1.2 | 0.9 | 0.5 – 1.5 | 29 | 1.0 | 0.6 | 0.2 – 1.5 | |
5 | 94 | 1.7 | 1.3 | 0.8 – 2.2 | 25 | 0.8 | 0.5 | 0.2 – 1.3 | |
P for trend = 0.39 | P for trend = 0.19 | ||||||||
B-Hexacholorocyclohexane | 1 | 77 | 1.0 | 1.0 | 26 | 1.0 | 1.0 | ||
2 | 93 | 1.0 | 0.8 | 0.5 – 1.3 | 22 | 0.8 | 0.7 | 0.3 – 1.7 | |
3 | 69 | 0.7 | 0.6 | 0.4 – 0.9 | 19 | 0.7 | 0.8 | 0.4 – 1.9 | |
4 | 66 | 0.7 | 0.5 | 0.3 – 0.8 | 23 | 0.6 | 0.5 | 0.2 – 1.3 | |
5 | 57 | 0.6 | 0.5 | 0.3 – 0.8 | 38 | 1.4 | 1.2 | 0.5 – 3.2 | |
P for trend = 0.01 | P for trend = 0.41 | ||||||||
Dieldrin | 1 | 45 | 1.0 | 1.0 | 21 | 1.0 | 1.0 | ||
2 | 67 | 1.4 | 1.4 | 0.8 – 2.3 | 24 | 1.1 | 0.9 | 0.4 – 2.1 | |
3 | 85 | 1.9 | 1.9 | 1.1 – 3.2 | 18 | 0.8 | 0.7 | 0.3 – 1.7 | |
4 | 82 | 1.7 | 1.8 | 1.0 – 3.0 | 30 | 1.0 | 0.7 | 0.3 – 1.7 | |
5 | 74 | 1.8 | 1.7 | 1.0 – 3.0 | 35 | 1.6 | 1.0 | 0.4 – 2.2 | |
P for trend = 0.12 | P for trend = 0.95 | ||||||||
Heptachlor Epoxide | 1 | 64 | 1.0 | 1.0 | 31 | 1.0 | 1.0 | ||
2 | 58 | 0.6 | 0.5 | 0.3 – 0.9 | 23 | 1.0 | 0.7 | 0.3 – 1.5 | |
3 | 75 | 0.9 | 0.7 | 0.4 – 1.1 | 20 | 0.8 | 0.6 | 0.2 – 1.4 | |
4 | 83 | 1.1 | 0.7 | 0.4 – 1.3 | 24 | 1.1 | 0.7 | 0.3 – 1.8 | |
5 | 72 | 1.0 | 0.5 | 0.3 – 1.0 | 28 | 0.9 | 0.9 | 0.3 – 3.0 | |
P for trend = 0.11 | P for trend = 0.98 | ||||||||
Hexachlorobenzene | 1+2 | 140 | 1.0 | 1.0 | 58 | 1.0 | 1.0 | ||
3 | 70 | 1.0 | 1.0 | 0.7 – 1.6 | 28 | 0.8 | 0.9 | 0.5 – 1.8 | |
4 | 85 | 0.9 | 0.8 | 0.5 – 1.3 | 17 | 0.4 | 0.3 | 0.1 – 0.6 | |
5 | 62 | 0.9 | 1.0 | 0.6 – 1.6 | 25 | 0.5 | 0.4 | 0.2 – 0.9 | |
P for trend = 0.72 | P for trend = 0.01 | ||||||||
trans-Nonachlor | 1+2 | 144 | 1.0 | 1.0 | 40 | 1.0 | 1.0 | ||
3 | 69 | 1.1 | 0.9 | 0.6 –1.4 | 33 | 1.3 | 1.1 | 0.5 –2.3 | |
4 | 71 | 0.9 | 0.8 | 0.5 – 1.3 | 28 | 0.9 | 0.6 | 0.3 – 1.4 | |
5 | 78 | 1.0 | 0.9 | 0.5 – 1.4 | 30 | 1.5 | 0.8 | 0.3 – 1.8 | |
P for trend = 0.51 | P for trend = 0.47 | ||||||||
Oxychlordane | 1+2 | 124 | 1.0 | 1.0 | 45 | 1.0 | 1.0 | ||
2 | 71 | 1.0 | 0.8 | 0.5 – 1.2 | 23 | 0.9 | 0.7 | 0.3 – 1.6 | |
3 | 70 | 1.2 | 1.0 | 0.6 – 1.5 | 27 | 1.0 | 0.8 | 0.4 – 1.8 | |
4 | 78 | 1.2 | 0.9 | 0.6 – 1.6 | 24 | 0.9 | 1.0 | 0.4 – 2.5 | |
P for trend = 0.93 | P for trend = 0.96 |
Number after restrictions for adjusted analyses
Adjusted for age groups (3 indicators), center (11 indicators), triglycerides (continuous), cholesterol (continuous), prepregnancy BMI (continuous), previous pregnancy with IPI < 2years (nullips in reference group), previous pregnancy with IPI >= 2 years, race (two indicator variables), SES (continuous), maternal age (2 indicators) and smoking status (4 indicators).