Skip to main content
. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Hypertension. 2014 May 5;64(1):178–184. doi: 10.1161/HYPERTENSIONAHA.114.03335

Figure 3. β-receptors mediate the effects of NE on NCC.

Figure 3

Panel A: Treatment with the α-receptor agonist, phenylephrine (PE), for 30 minutes did not significantly increase pNCC-T53. Total NCC abundance also remained unchanged. n=5 per group. Panel B: Treatment with the β-receptors agonist, isoproterenol (Iso), for 30 minutes significantly increased pNCC-T53 abundance. p<0.05 by unpaired t-test. Total NCC abundance remained unchanged. n=4 per group. Panel C: Treatment with both agonists together increased pNCC-T53 abundance greater than either agonist alone. p<0.016 by unpaired t-test. Total NCC abundance remained unchanged. n= 5 for the Control and Iso groups and 4 for the Iso+PE group. See online supplement for densiometry.