Table 3.
Associations between placenta OTCs and weight/length gain across OTC categories in weighted linear regressiona
|
Organotin compound |
Conc. (ng/g fw) |
Weight gain 0–3 months |
|
Weight gain 3–18 months |
|
||||
|---|---|---|---|---|---|---|---|---|---|
| N | Weight gain (kg/week) | β (95% CI) | p | N | Weight gain (kg/week) | β (95% CI) | p | ||
| DBT |
<0.10 |
31 |
0.220 |
ref |
|
27 |
0.087 |
ref |
|
| |
0.10–0.14 |
30 |
0.222 |
0.016 (−0.011, 0.044) |
0.23 |
26 |
0.082 |
−0.007 (−0.020, 0.006) |
0.29 |
| |
≥0.15 |
41 |
0.230 |
0.021 (0.000, 0.043) |
0.054 |
33 |
0.079 |
−0.009 (−0.020, 0.002) |
0.11 |
| TBT |
<0.10 |
31 |
0.224 |
ref |
|
26 |
0.086 |
ref |
|
| |
0.10–0.4 |
39 |
0.217 |
0.005 (−0.018, 0.029) |
0.64 |
34 |
0.084 |
−0.007 (−0.022, 0.008) |
0.36 |
| |
>0.4 |
32 |
0.235 |
0.024 (0.003, 0.044) |
0.024 |
26 |
0.078 |
−0.011 (−0.024, 0.003) |
0.12 |
| TPhT |
<0.02 |
60 |
0.227 |
ref |
|
49 |
0.080 |
ref |
|
| |
≥0.02 |
42 |
0.220 |
0.005 (−0.016, 0.027) |
0.62 |
37 |
0.085 |
0.002 (−0.008, 0.011) |
0.74 |
| Sum of OTCs |
<0.25 |
26 |
0.220 |
ref |
|
22 |
0.083 |
ref |
|
| |
0.25–0.50 |
31 |
0.228 |
0.025 (−0.002, 0.052) |
0.065 |
27 |
0.086 |
<0.001 (−0.016, 0.016) |
1.00 |
| |
>0.50 |
45 |
0.225 |
0.018 (−0.001, 0.037) |
0.062 |
37 |
0.080 |
−0.008 (−0.021, 0.005) |
0.21 |
|
Organotin compound |
Conc. (ng/g fw) |
Length gain 0–3 monhts |
|
Length gain 3–18 monhts |
|
||||
| |
|
N |
Length gain (cm/week) |
β (95% CI) |
p |
N |
Length gain (cm/week) |
β (95% CI) |
p |
| DBT |
<0.10 |
32 |
0.83 |
ref |
|
28 |
0.34 |
ref |
|
| |
0.10–0.14 |
30 |
0.83 |
0.054 (−0.038, 0.146) |
0.25 |
26 |
0.33 |
−0.014 (−0.039, 0.010) |
0.25 |
| |
≥0.15 |
41 |
0.83 |
0.047 (−0.021, 0.114) |
0.18 |
33 |
0.33 |
−0.008 (−0.027, 0.011) |
0.42 |
| TBT |
<0.10 |
32 |
0.82 |
ref |
|
27 |
0.34 |
ref |
|
| |
0.10–0.4 |
39 |
0.83 |
−0.015 (−0.085, 0.055) |
0.67 |
34 |
0.33 |
−0.025 (−0.048, −0.001) |
0.042 |
| |
>0.4 |
32 |
0.84 |
0.024 (−0.038, 0.085) |
0.45 |
26 |
0.34 |
−0.014 (−0.036, 0.009) |
0.22 |
| TPhT |
<0.02 |
60 |
0.83 |
ref |
|
49 |
0.34 |
ref |
|
| |
≥0.02 |
43 |
0.83 |
−0.005 (−0.061, 0.051) |
0.86 |
38 |
0.34 |
−0.006 (−0.025, 0.013) |
0.54 |
| Sum of OTCs |
<0.25 |
27 |
0.84 |
ref |
|
23 |
0.34 |
ref |
|
| |
0.25–0.50 |
31 |
0.82 |
0.012 (−0.084, 0.108) |
0.81 |
27 |
0.34 |
−0.012 (−0.042, 0.018) |
0.41 |
| >0.50 | 45 | 0.83 | 0.018 (−0.039, 0.076) | 0.53 | 37 | 0.33 | −0.012 (−0.035, 0.010) | 0.29 | |
aAdjusted for maternal age at birth, maternal pregnancy body mass index, diabetes (yes/no) and smoking (yes/no) during pregnancy, and infant weight for gestational age.