Table 4.
Associations between categorical OTC concentrations and PI from linear regression analysis weighted for sampling fractionsa
| Organotin compound | Conc (ng/g fw) |
PI at birth |
|
PI at 3 months |
|
PI at 18 monhts |
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | mean PI (kg/m3) | β (95% CI) | p | N | mean PI (kg/m3) | β (95% CI) | p | N | mean PI (kg/m3) | β (95% CI) | p | ||
| DBT |
<0.10 |
33 |
26.8 |
ref |
|
31 |
27.5 |
ref |
|
28 |
20.1 |
ref |
|
| |
0.10–0.14 |
30 |
26.0 |
−1.46 (−2.56, −0.35) |
0.010 |
|
26.7 |
−1.35 (−2.77, 0.08) |
0.063 |
|
20.0 |
−0.79 (−2.36, 0.79) |
0.32 |
| |
≥0.15 |
42 |
27.4 |
−0.45 (−1.55, 0.66) |
0.43 |
30 41 |
28.2 |
−0.10 (−1.15, 1.13) |
0.99 |
26 33 |
20.0 |
−0.93 (−2.04, 0.18) |
0.098 |
| TBT |
<0.10 |
33 |
26.5 |
ref |
|
31 |
27.4 |
ref |
|
27 |
20.0 |
ref |
|
| |
0.10–0.39 |
40 |
26.6 |
−1.36 (−2.90, 0.18) |
0.084 |
39 |
26.9 |
−0.28 (−1.79, 1.24) |
0.72 |
|
20.2 |
0.46 (−0.97, 1.90) |
0.52 |
| |
≥0.40 |
32 |
27.5 |
−0.26 (−1.63, 1.12) |
0.71 |
32 |
28.5 |
0.85 (−0.20, 1.90) |
0.11 |
34 26 |
19.9 |
−0.38 (−1.33, 0.57) |
0.43 |
| TPhT |
<0.02 |
61 |
27.0 |
ref |
|
60 |
27.9 |
ref |
|
49 |
20.1 |
ref |
|
| |
≥0.02 |
44 |
26.6 |
−0.75 (−1.56, 0.06) |
0.068 |
42 |
27.0 |
−0.24 (−1.20, 0.73) |
0.63 |
38 |
20.1 |
0.21 (−0.67, 1.09) |
0.63 |
| Sum of OTCs |
<0.25 |
27 |
27.1 |
ref |
|
26 |
27.3 |
ref |
|
23 |
19.8 |
ref |
|
| |
0.25–0.49 |
32 |
26.0 |
−1.23 (−2.69, 0.24) |
0.10 |
31 |
27.2 |
0.57 (−1.03, 2.16) |
0.48 |
|
20.3 |
1.33 (−0.31, 2.97) |
0.11 |
| ≥0.50 | 46 | 27.3 | −0.53 (−1.79, 0.74) | 0.41 | 45 | 27.9 | 0.42 (−0.59, 1.43) | 0.41 | 27 37 | 20.0 | −0.33 (−1.27, 0.60) | 0.48 | |
aAdjusted for maternal age at birth, maternal pregnancy body mass index, diabetes (yes/no) and smoking (yes/no) during pregnancy, and infant weight for gestational age.