Table 1.
Clinicopathologic Features and Methylation Status in 107 CRC Patients.
| Clinical Parameters | Number | CXCL14 Methylation Status | p-value# | |
|---|---|---|---|---|
| Methylated 85 (79.4%) | Unmethylated 22 (20.6%) | |||
| Gender | ||||
| Male | 71 | 56 (78.9%) | 15 (21.1%) | |
| Female | 36 | 28 (77.8%) | 8 (22.2%) | p=0.90 |
| Age | ||||
| ≥60 | 53 | 45 (84.9%) | 8 (15.1%) | |
| <60 | 54 | 40 (74.1%) | 14 (25.9%) | p=0.17 |
| TNM stage | ||||
| I | 15 | 10 (66.7%) | 5 (33.3%) | |
| II | 44 | 38 (86.4%) | 6 (13.6%) | p>0.05 |
| III | 48 | 37 (77.1%) | 9 (22.9%) | |
| IV | 0 | |||
| Tumor size (cm) | ||||
| ≥5 | 60 | 50 (83.3%) | 10 (16.7%) | |
| <5 | 47 | 35 (74.5%) | 12 (25.5%) | p=0.26 |
| Differentiation | ||||
| Poor | 22 | 17 (77.3%) | 5 (22.7%) | |
| Moderate | 78 | 63 (80.8%) | 15 (19.2%) | p>0.05 |
| Well | 7 | 5 (71.4%) | 2 (8.6%) | |
| Lymphatic metastasis | ||||
| Negative | 58 | 47 (81.0%) | 11 (19.0%) | |
| Positive | 49 | 38 (77.6%) | 11 (22.4%) | p=0.66 |
Note:
#
p-value is obtained from χ2 test. p<0.05 is statistically significant.