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. 2014 Jun 18;8:51. doi: 10.3389/fnint.2014.00051

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Copyright © 2014 Carmel and Martin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Motor cortex stimulation causes robust outgrowth to the magnocellular red nucleus. Heatmaps showing corticorubral axon density in the magnocellular red nucleus after injury alone (A) and injury plus stimulation (B). Color scales apply to both (A,B). Note the axon length scales are different on the two sides to show the full range on each side. (C) Schematic organization of corticorubral system and stimulation. Outgrowth to the contralateral nucleus (right) could improve motor control on the impaired side through the re-crossed rubrospinal tract. Modified from Carmel et al. (2013).