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. 2013 Sep 16;3(3):1374–1394. doi: 10.3390/brainsci3031374

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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A low magnification, longitudinal plane field of a resin embedded thin section of optic nerve at 2 h after an acute stretch-injury (19–22 ms period of mechanical loading). Two astrocyte cell bodies (A) are visible. Bundles of astrocyte intermediate filaments (GFAP) (arrow) occur within astrocyte processes (black arrows) extending between myelinated nerve fibres. A large, damaged nerve fibre with a lucent axoplasm and numerous irregular myelin discontinuities (md—white arrows) is visible in the centre of this field. Closer examination of the field reveals numerous lucent and dark md in the myelin sheaths of neighboring, smaller nerve fibers (dotted white arrows). Magnification 2300×.