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. 2014 Jun 1;12(2):66–75. doi: 10.1089/lrb.2013.0045

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Copyright 2014, Mary Ann Liebert, Inc.

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FIG. 2. — Electrophysiological characteristics of rat mesenteric lymphatic muscle in a wire myograph-mounted isolated vessel. (A) Original recordings of membrane potential (top trace) displaying APs (illustrated on an expanded scale in 1) and correlated isometric contractions in a vessel stretched to 0.2 mN preload (bottom trace). Administration of nifedipine (1 μM, horizontal bar) inhibited the contractions and APs, unmasking STDs (as evident on an expanded scale in 2). (B) Original recordings of membrane potential (top trace) and force (bottom trace) under control conditions (left) and in the presence of niflumic acid (NFA, 50 μM). Traces are representative of 4–10 experiments.