Table 2.

Astigmatism and anterior corneal aberration values in 10 patient models before and after simulated refractive CXL using a linear bow-tie treatment (pattern 4) with 2x corneal stiffening aligned on the flat axis of astigmatism.

	Pretreatment				Posttreatment				Change
	Ksteep (D)	Kflat (D)	LOA RMS (μm)	HOA RSM (μm)	Ksteep (D)	Kflat (D)	LOA RMS (μm)	HOA RSM (μm)	Ksteep (D)	Kflat (D)	LOA RMS (μm)	HOA RSM (μm)
Patient
1	42.79	40.10	1.19	0.06	42.13	40.54	0.56	0.11	–0.66	0.44	–0.63	0.05
2	44.12	41.91	0.96	0.14	43.48	42.39	0.34	0.16	–0.64	0.48	–0.62	0
3	47.96	44.04	1.99	0.22	47.37	44.57	1.45	0.23	–0.59	0.53	–0.54	0
4	44.18	41.11	1.26	0.18	43.55	41.58	0.78	0.23	–0.63	0.47	–0.48	0.05
5	43.91	42.64	0.64	0.16	43.5	43.15	0.20	0.16	–0.41	0.51	–0.44	0
6	43.11	40.36	1.18	0.06	42.34	40.68	0.61	0.10	–0.77	0.32	–0.57	0.04
7	45.40	43.02	1.40	0.24	44.94	43.3	1.24	0.25	–0.46	0.28	–0.16	0
8	44.07	41.97	0.91	0.20	43.42	42.47	0.43	0.22	–0.65	0.50	–0.48	0.02
9	44.00	41.21	1.11	0.21	43.38	41.69	0.67	0.25	–0.62	0.48	–0.44	0.04
10	46.20	44.80	0.68	0.21	45.74	45.57	0.29	0.21	–0.46	0.77	–0.39	0.00
Statistic
Mean	44.57	42.12	1.13	0.17	43.99	42.59	0.66	0.19	–0.59	0.48	–0.48	0.02
SD	1.55	1.53	0.39	0.06	1.60	1.61	0.41	0.06	0.11	0.13	0.14	0.02
P value*	—	—	—	—	—	—	—	—	<.001	<.001	<.001	<.001

HOA RMS = higher-order root-mean-square aberrations calculated for a 4.0 mm pupil; Kflat = simulated keratometry value for flat meridian; Ksteep = simulated keratometry value for steep meridian; LOA RMS = lower-order root-mean-square aberrations

^*Student t test on pretreatment – posttreatment values