Table 4.

Astigmatism in 10 patient models with fiber-independent and fiber dependent material formulations before and after simulated refractive crosslinking using a linear bow-tie treatment (pattern 4) with 2x corneal stiffening aligned on the flat axis of astigmatism.

	Fiber-Independent Material Model								Fiber-Dependent Material Model
	Pretreatment (D)		Posttreatment (D)		Change (D)				Posttreatment (D)		Change (D)
Parameter	Ksteep	Kflat	Ksteep	Kflat	Ksteep	Kflat	Astig	Ratio	Ksteep	Kflat	Ksteep	Kflat	Astig	Flattening Ratio
Patient
1	42.79	40.10	42.13	40.54	–0.66	0.44	–1.10	0.66	42.01	40.4	–0.78	0.30	–1.08	0.38
2	44.12	41.91	43.48	42.39	–0.64	0.48	–1.12	0.75	43.39	42.21	–0.73	0.30	–1.03	0.41
3	47.96	44.04	47.37	44.57	–0.59	0.53	–1.12	0.89	47.32	44.36	–0.64	0.32	–0.96	0.50
4	44.18	41.11	43.55	41.58	–0.63	0.47	–1.10	0.74	43.53	41.41	–0.65	0.30	–0.95	0.46
5	43.91	42.64	43.5	43.15	–0.41	0.51	–0.92	1.24	43.28	42.9	–0.63	0.26	–0.89	0.41
6	43.11	40.36	42.34	40.68	–0.77	0.32	–1.09	0.41	42.3	40.69	–0.81	0.33	–1.14	0.40
7	45.40	43.02	44.94	43.3	–0.46	0.28	–0.74	0.60	44.62	43.45	–0.78	0.43	–1.21	0.55
8	44.07	41.97	43.42	42.47	–0.65	0.50	–1.15	0.76	43.37	42.27	–0.70	0.30	–1.00	0.42
9	44.00	41.21	43.38	41.69	–0.62	0.48	–1.10	0.77	43.34	41.51	–0.66	0.30	–0.96	0.45
10	46.20	44.80	45.74	45.57	–0.46	0.77	–1.23	1.67	45.68	45.4	–0.52	0.60	–1.12	1.15
Statistic
Mean	44.57	42.12	43.99	42.59	–0.59	0.48	–1.07	0.85	43.88	42.46	–0.69	0.34	–1.03	0.52
SD	1.55	1.53	1.60	1.61	0.11	0.13	0.14	0.36	1.59	1.60	0.09	0.10	0.10	0.23
P value*	—	—	—	—	<.001	<.001	—	—	—	—	<.001	—	.5	—

Astig = asigmatism; Kflat = keratometry in flat meridian; Ksteep = keratometry in steep meridian

^*Student t test on pretreatment – posttreatment values