Table 4.
Subject and seizure characteristics by acute neurologic diagnosis.
| Variable | All Diagnoses (N=550) |
Specific Acute Neurologic Diagnosis N (%) |
|||
|---|---|---|---|---|---|
| Traumatic Brain Injury (N=61) |
Hypoxic Ischemic Encephalopathy (N=71) |
Stroke (N=33) |
p-value | ||
| Age (median and IQR) | 36.5 (9-122) | 11.5 (4-80.5) | 24 (5-132) | 50 (4.3-157) | 0.2601 |
| Age Groups | 0.029 | ||||
| <2 months | 21 (4%) | 1 (2%) | 5 (7%) | 4 (12%) | |
| 2 months-1 year | 133 (24%) | 29 (48%) | 20 (28%) | 6 (18%) | |
| 1 year - 10 years | 253 (46%) | 17 (28%) | 27 (38%) | 10 (30%) | |
| >10 years | 143 (26%) | 14 (23%) | 19 (27%) | 13 (28%) | |
| Sex (male) | 295 (54%) | 36 (59%) | 38 (54%) | 14 (42%) | 0.306 |
| Prior Developmental Delay / Intellectual Disability | 227 (41%) | 3 (5%) | 20 (28%) | 6 (18%) | 0.001 |
| Prior Epilepsy | 174 (32%) | 4 (7%) | 6 (8%) | \ | 0.306 |
| Seizure Prior to CEEG | 162 (29%) | 17 (28%) | 27 (38%) | 13 (39%) | 0.377 |
| Mental Status at CEEG | <0.001 | ||||
| Normal | 71 (13%) | 7 (14%) | 1 (1%) | 2 (6%) | |
| Lethargic/Obtunded | 297 (56%) | 22 (44%) | 25 (36%) | 16 (50%) | |
| Comatose | 158 (30%) | 21 (42%) | 43 (62%) | 14 (44%) | |
| Initial CEEG Background | 0.003 | ||||
| Normal | 94 (17%) | 17 (28%) | 6 (8%) | 4 (12%) | |
| Slow/Disorganized | 337 (61%) | 30 (49%) | 26 (37%) | 21 (64%) | |
| Discontinuous | 38 (7%) | 5 (8%) | 11 (15%) | 4 (12%) | |
| Burst-Suppression | 29 (5%) | 3 (5%) | 11 (15%) | 2 (6%) | |
| Attenuated/Featureless | 52 (9%) | 6 (10%) | 17 (24%) | 2 (6%) | |
| Mortality (died) | 73 (13%) | 11 (18%) | 26 (37%) | 4 (12%) | 0.009 |
| CEEG Monitoring Duration | 0.183 | ||||
| <12 hours | 88 (16%) | 6 (10%) | 8 (11%) | 4 (13%) | |
| 12-24 hours | 187 (35%) | 16 (26%) | 14 (20%) | 10 (31%) | |
| 25-48 hours | 129 (24%) | 12 (20%) | 18 (26%) | 13 (41%) | |
| 49-72 hours | 44 (8%) | 11 (18%) | 13 (19%) | 1 (3%) | |
| >72 hours | 94 (17%) | 16 (26%) | 17 (24%) | 4 (13%) | |
| Electrographic Seizures | 162 (29%) | 18 (30%) | 12 (17%) | 10 (30%) | 0.16 |
| Electrographic Status Epilepticus | 61 (38%) | 10 (16%) | 5 (7%) | 3 (9%) | 0.227 |
| Seizure Clinical Correlate | 0.434 | ||||
| All (100%) | 43 (27%) | 3 (17%) | 1 (8%) | \ | |
| Most (50-99%) | 22 (14%) | 4 (22%) | \ | 1 (11%) | |
| Some (1-49%) | 33 (21%) | 4 (22%) | 3 (25%) | 2 (22%) | |
| None (0%) | 59 (38%) | 7 (39%) | 8 (67%) | 6 (67%) | |
| Seizure Duration | 0.879 | ||||
| <1 minute | 60 (38%) | 5 (28%) | 4 (33%) | 2 (20%) | |
| 1-5 minutes | 63 (40%) | 6 (33%) | 6 (50%) | 4 (40%) | |
| 6-30 minutes | 25 (16%) | 6 (33%) | 2 (17%) | 3 (30%) | |
| >30 minutes | 10 (6%) | 1 (6%) | \ | 1 (10%) | |
| Seizure Onset Distribution | |||||
| Focal | 97 (57%) | 12 (67%) | 5 (42%) | 9 (90%) | 0.013 |
| Multi-Focal | 34 (20%) | 4 (22%) | 3 (25%) | 1 (10%) | 0.805 |
| Generalized | 39 (23%) | 2 (11%) | 4 (33%) | \ | 0.427 |
| Seizure Maximal Distribution | |||||
| Focal-Unilateral | 85 (53%) | 13 (72%) | 6 (46%) | 9 (90%) | 0.031 |
| Bilateral | 76 (47%) | 5 (28%) | 7 (52%) | 1 (10%) | 0.53 |
Legend: \ = no data