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. Author manuscript; available in PMC: 2015 Mar 20.
Published in final edited form as: Mol Cell. 2014 Mar 13;53(6):1031–1043. doi: 10.1016/j.molcel.2014.02.013

Figure 7. Repression by miR-22 shapes the 3'UTR landscape.

Figure 7

(A–E) Influence of miR-22 targeting on 3'UTR isoform usage. Weighted 3'UTR lengths were determined using 3P-seq data from heart (A), liver (B), muscle (C), kidney (D) and WAT (E). Plotted are the cumulative distributions of the differences in lengths (subtracting that of the wild-type tissue from that of the miR-22Δ tissue) for genes with control sites in the variable region (grey) and those with miR-22 sites in the variable region (red). Significance was determined using the Kolmogorov-Smirnov test.