Table 2.

Genotype and variant allele frequencies for rs846910: G>A and rs45487298: insA polymorphisms.

Polymorphism	Genotype	MetS patients		Controls		P1
		N (%)	Mutated allele frequency	N (%)	Mutated allele frequency
rs846910: G>A	G/G	35 (83.3%)		34 (79.1%)
	G/A	7 (16.7%)	0.08	9 (20.9%)	0.10	0.615
	A/A	0 (0%)		0 (0%)
	Total	42		43
	P2	0.841		0.745
rs45487298: insA	N/N3	26 (63.4%)		25 (58.1%)
	N/insA	14 (34.1%)	0.20	16 (37.2%)	0.23	0.930
	insA/insA	1 (2.4%)		2 (4.7%)
	Total	41		43
	P2	0.856		0.962

¹significance of χ² / Fisher’s exact test for comparison of genotype frequencies between MetS patients and controls.

²P-value for Hardy-Weinberg equilibrium.

³N – wild-type allele of rs45487298: insA.