Figure 1.
Clinical features of ocular inflammation in Stat6VT mice. (A) Photographs showing blepharitis in Stat6VT mouse (right: arrow denotes lid edema) compared with unaffected WT control (left). Scale: 5 mm. (B) Cumulative incidence of blepharitis in Stat6VT mice (n = 20, 24 respectively for Stat6VT and WT). (C) Slit-lamp photographs of WT and Stat6VT mice showing diffuse corneal neovascularization in Stat6VT mouse (arrow). Scale: 500 μm. (D) Behavioral assay with video recording determined the rate of grooming versus lid scratching over a 30-minute period in both WT and Stat6VT transgenic mice (n = 5, 7 respectively of WT and Stat6VT). Counts were obtained by two independent observers; *P < 0.05).
