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. 2014 Jun 18;9(6):e99724. doi: 10.1371/journal.pone.0099724

Table 4. Association analysis of rs9276370 with clinical classifications in HBsAg positive carriers.

Clinical characteristic Genotype Frequency for the group of interest MAF Genotype Frequency for the other two groups MAF Trend test P-value Testing for mode of inheritance P-valuea OR (95% CI)a
GG GT TT GG GT TT
PNALT 0.011 0.164 0.825 0.093 0.004 0.132 0.865 0.069 0.0241 Additive 0.0376 0.73 (0.55–0.96)
Dominant 0.0667 1.32 (0.98–1.78)
Recessive 0.0947 3.09 (0.82–11.63)
CHB 0.000 0.146 0.854 0.073 0.011 0.136 0.853 0.079 0.5247 Additive 0.3746 1.13 (0.87–1.47)
Dominant 0.7610 0.96 (0.72–1.27)
Recessive 0.9719 N/A
HCC 0.011 0.101 0.888 0.062 0.004 0.153 0.843 0.080 0.0923 Additive 0.2134 1.25 (0.88–1.76)
Dominant 0.0903 1.38 (0.95–2.00)
Recessive 0.0896 3.25 (0.83–12.70)
a

ORs and CIs were calculated by setting the T allele as the reference with age adjustment.