Table 3. Summary of significantly enriched GO terms from the Ontologizer and GO-Elite analyses that are relevant to kidney development.

GO ID	GO Term Name	Observed in Ontologizer (O);GO-Elite (G)	Rank 2012 n = 127 (O), n = 85 (G)	Rank 2009 n = 48 (O), n = 21 (G)
GO:0032835	glomerulus development	G	1	n/a
GO:0061005	cell differentiation involved in kidney development	G	2	n/a
GO:0001655	urogenital system development	O	10	14
>GO:2001012	mesenchymal cell differentiation involved in renal system development	O	90	n/a
>GO:0001657	ureteric bud development	O	65	n/a
GO:0003014	renal system process	O, G	52(O); 25(G)	n/a
>GO:0097205	renal filtration	O	43	n/a
GO:0001763	morphogenesis of a branching structure	O	64	42
>GO:0048754	branching morphogenesis of an epithelial tube	G	43	n/a

A summary of the significantly enriched GO terms from the Ontologizer [28] and GO-Elite [27] analyses, which are relevant to kidney development, using the pre-annotation (2009; Tables S2–S5 in File S1) and post-annotation datasets (2012; Tables S6–S9, in File S1). Terms in italics indicate parent terms where the descendants are indicated directly underneath as follows: > descendant of term above in italics. Rank refers to the position of the term in the results of the enrichment analyses (see Tables S2–S9 in File S1) where significance of the enriched term has a p-value of <0.1. (n/a = not applicable).