Table 3. Summary of significantly enriched GO terms from the Ontologizer and GO-Elite analyses that are relevant to kidney development.
GO ID | GO Term Name | Observed in Ontologizer (O);GO-Elite (G) | Rank 2012 n = 127 (O), n = 85 (G) | Rank 2009 n = 48 (O), n = 21 (G) |
GO:0032835 | glomerulus development | G | 1 | n/a |
GO:0061005 | cell differentiation involved in kidney development | G | 2 | n/a |
GO:0001655 | urogenital system development | O | 10 | 14 |
>GO:2001012 | mesenchymal cell differentiation involved in renal system development | O | 90 | n/a |
>GO:0001657 | ureteric bud development | O | 65 | n/a |
GO:0003014 | renal system process | O, G | 52(O); 25(G) | n/a |
>GO:0097205 | renal filtration | O | 43 | n/a |
GO:0001763 | morphogenesis of a branching structure | O | 64 | 42 |
>GO:0048754 | branching morphogenesis of an epithelial tube | G | 43 | n/a |
A summary of the significantly enriched GO terms from the Ontologizer [28] and GO-Elite [27] analyses, which are relevant to kidney development, using the pre-annotation (2009; Tables S2–S5 in File S1) and post-annotation datasets (2012; Tables S6–S9, in File S1). Terms in italics indicate parent terms where the descendants are indicated directly underneath as follows: > descendant of term above in italics. Rank refers to the position of the term in the results of the enrichment analyses (see Tables S2–S9 in File S1) where significance of the enriched term has a p-value of <0.1. (n/a = not applicable).