Table 2. Summary of SNPs in GADD45a gene.

SNP ID	Positiona	Locationb	Allele	Frequ ency AAc	Frequency EAc	Tagging SNP
rs1511686	68,148,921	c.-318-1939	T>A	0.13	0.00
–	68,149,189	c.-318-1671	G>A	0.00	0.03
rs115517134	68,149,321	c.-318-1539	A>G	0.03	0.00
rs188178283	68,150,258	c.-318-602	G>T	0.00	0.03
rs581000	68,150,271	c.-318-589	G>C	0.37	0.13	**
rs3783456	68,150,622	c.-318-238	A>G	0.03	0.00
rs3783457	68,150,673	c.-318-187	C>A	0.03	0.00
–	68,150,681	c.-318-179	C>G	0.03	0.00
rs1397946	68,150,898	c.-280	A>T	0.13	0.00	**
rs3783460	68,150,931	c.-247	T>G	0.03	0.00
rs3783462	68,151,227	c.44+6	T>A	0.03	0.00
rs3783465	68,151,645	c.45-63	G>A	0.03	0.00
rs3783466	68,151,685	c.45-23	C>T	0.17	0.13
rs2759219	68,151,980	c.147-53	G>T	0.3	0.13	**
rs149179509	68,152,171	c.285	G>A	0.00	0.03
rs3783468	68,152,363	c.384+93	G>A	0.23	0.57	**
rs3783469	68,152,386	c.384+116	T>C	0.03	0.13	**
rs681673	68,152,388	c.384+118	C>T	0.5	0.27
rs532446	68,152,438	c.384+168	T>C	0.5	0.27	**
rs3783472	68,152,558	c.384+288	G>C	0.03	0.00
rs143275022	68,152,736	c.384+466	del T	0.00	0.03
rs3171012	68,153,206	c.385-138	T>C	0.17	0.13	**
rs3046000	68,153,271–68,153,279	c.385-73_385-65	del (9nt)	0.1	0.00	**
rs3783478#	68,153,451	c.492	A>G	0.13	0.00	**
rs3783479	68,153,484	c.*27	C>T	0.03	0.00
rs607375	68,154,086	c. * 564+65	C>G	0.4	0.27	**
rs3783482	68,154,204	c.*564+183	C>T	0.03	0.00
rs3783483	68,154,208	c.*564+187	G>A	0.07	0.00	**
rs606470	68,154,299	c. * 564+278	T>C	0.23	0.03	**
rs77985416	68,154,373	c.*564+352	G>A	0.03	0.00
Rs78379425	68,154,466	c.*564+445	G>A	0.03	0.00

^aPosition on chromosome 1 according to NCBI Build 37.

^bLocation relative to reference sequence NM_001924.3.

^cRepresents minor allele frequency in gene resequencing data in 15 African American (AA) and 15 European American (EA).

Boldface highlights SNPs genotyped in both Chicago and Spanish study.

** Represents tagging SNP.

* Represents 3′UTR region.

# represents synonymous SNP (Glu164Glu).