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. 2014 Jun 18;9(6):e100129. doi: 10.1371/journal.pone.0100129

Figure 1. Effect of early phase BSE-CD treatment on hepatic granulomatous inflammation in mice infected with S. japonicum.

Figure 1

Mice were infected with 20±2 cercariae, Treatment with BSE-CD or placebo from week 5 to week 7. Mice were killed, and liver tissues were fixed by formalin and stained with H&E. (A) Liver tissues stained with H&E. (B) Hepatic egg granuloma size was measured by computer-assisted histomorphometric analysis. All data are expressed as mean ± SEM (n = 8 for each group). *P<0.05 versus corresponding infected mice or the cyclodextrin (280 mg/kg) group.