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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Urol Oncol. 2014 May 16;32(5):657–662. doi: 10.1016/j.urolonc.2014.02.003

Figure 1.

Figure 1

A (H&E). Urothelial carcinoma in situ composed of large and pleomorphic tumor cells. Mitotic figures present. B (PTEN). Loss of PTEN expression (0 intensity) in tumor cells (arrows) compared to adjacent non-neoplastic urothelium. C (p-S6). Tumor cells with strong expression (3+ intensity) of p-S6 compared to adjacent non-neoplastic urothelium. D (p-Akt). Increased expression of p-Akt (2+ intensity) in tumor cells.