. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: Pediatr Res. 2014 Apr 8;76(1):86–92. doi: 10.1038/pr.2014.45

Table 2. Diffusion parameters for 7-year-old VPT children with and without moderate-severe WMA.

Parameter	Tract	Mod-Severe WMA n=20	No WMA n=42	p-value^a ^*
FA	Left CST	0.64 ± 0.03	0.64 ± 0.03	0.95
	Right CST	0.57 ± 0.03	0.58 ± 0.03	0.54
	Corpus Callosum	0.65 ± 0.03	0.68 ± 0.02	0.0002

MD	Left CST	0.76 ± 0.02	0.76 ± 0.02	0.44
	Right CST	0.90 ± 0.07	0.85 ± 0.06	0.008
	Corpus Callosum	1.07 ± 0.08	1.02 ± 0.07	0.008

AD	Left CST	1.43 ± 0.04	1.42 ± 0.04	0.43
	Right CST	1.53 ± 0.10	1.46 ± 0.07	0.009
	Corpus Callosum	1.90 ± 0.10	1.88 ± 0.07	0.50

RD	Left CST	0.43 ± 0.03	0.43 ± 0.03	0.74
	Right CST	0.59 ± 0.07	0.54 ± 0.06	0.02
	Corpus Callosum	0.66 ± 0.08	0.59 ± 0.07	0.0007

Abbreviations: Fractional Anisotropy (FA), Mean Diffusivity (MD), Axial Diffusivity (AD), Radial Diffusivity (RD).

FA is dimensionless. Units for MD, AD and RD are 10^-3 mm²/s.

Adjusted for gender, gestational age at birth and age at scan for all tracts. Additional adjustment for handedness was done only in the CST tracts.

Bold text denotes significant between group differences following multiple comparisons correction with a level of significance determined at p ≤ 0.01.