Table 3. Diffusion parameters for 7-year-old VPT children with moderate-severe WMA categorized by motor outcome.
Parameter | Tract | Impaired MABC2 n=8 | Normal MABC2 n=12 | p-valuea* |
---|---|---|---|---|
FA | Left CST | 0.65 ± 0.03 | 0.64 ± 0.02 | 0.71 |
Right CST | 0.59 ± 0.02 | 0.56 ± 0.03 | 0.16 | |
Corpus Callosum | 0.63 ± 0.03 | 0.66 ± 0.02 | 0.01 | |
| ||||
MD | Left CST | 0.76 ± 0.01 | 0.76 ± 0.03 | 0.89 |
Right CST | 0.91 ± 0.05 | 0.90 ± 0.08 | 0.63 | |
Corpus Callosum | 1.09 ± 0.10 | 1.06 ± 0.06 | 0.75 | |
| ||||
AD | Left CST | 1.44 ± 0.05 | 1.42 ± 0.04 | 0.68 |
Right CST | 1.57 ± 0.08 | 1.51 ± 0.10 | 0.80 | |
Corpus Callosum | 1.89 ± 0.11 | 1.91 ± 0.09 | 0.27 | |
| ||||
RD | Left CST | 0.43 ± 0.02 | 0.43 ± 0.03 | 0.67 |
Right CST | 0.58 ± 0.04 | 0.59 ± 0.08 | 0.37 | |
Corpus Callosum | 0.69 ± 0.10 | 0.64 ± 0.05 | 0.17 |
Abbreviations: Fractional Anisotropy (FA), Mean Diffusivity (MD), Axial Diffusivity (AD), Radial Diffusivity (RD).
FA is dimensionless. Units for MD, AD and RD are 10-3 mm2/s.
Adjusted for gender, gestational age at birth and age at scan for all tracts. Additional adjustment for handedness was done only in the CST tracts.
Bold text denotes significant between group differences following multiple comparisons correction with a level of significance determined at p ≤ 0.01.