. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: Pediatr Res. 2014 Apr 14;76(1):100–108. doi: 10.1038/pr.2014.48

Table 4.

Summary statistics for cytokine concentrations in cases prior to NEC vs. controls summarized by day of measurement

Cytokine	Cases before onset of NEC					Controls					p-value
Cytokine	N	Min	Median	Mean	Max	n	Min	Median	Mean	Max	p-value

	*Postnatal Day 1*

BDNF	61	342	2741	3658	26312	470	206	3438	4453	103033	0.04
TGF-β	61	50	1090	1272	7305	470	56	1301	1586	7380	0.02

	*Postnatal Day 3*

IL-18	90	247	1066	1503	6016	837	6	1255	1549	7077	0.02
MIP-1α/CCL3	90	6	124	705	19945	837	6	154	677	50534	0.02
MMP-9	90	21149	751355	1827173	37067238	837	21096	1087801	2294486	185309104	0.01
RANTES/CCL5	90	2159	63127	74585	417270	837	1590	75081	94666	678668	0.03
TGF-β	90	50	988	1205	6869	836	0	1286	1540	7095	0.03

	*Postnatal Day 7*

MIP-1α/CCL3	86	6	120	762	16739	747	6	141	659	35707	0.02
RANTES/CCL5	86	4411	69165	80531	417052	747	666	84589	109406	1303609	0.01
TGF-β	86	50	1073	1376	5364	748	9	1487	1697	6978	0.01

	*Postnatal Day 14*

IL-2	68	3	25	36	155	808	3	37	54	616	0.01
IL-4	68	3	78	104	693	805	1	97	134	2560	0.04
TGF-β	68	50	1573	1855	5677	808	50	1952	2259	10022	0.04

	*Postnatal Day 21*

IL-2	52	3	24	35	171	748	2	38	54	560	0.04
IL-17	52	3	107	163	737	748	1	153	229	2330	0.04
BDNF	52	425	5309	9808	80448	749	24	7176	10468	239635	0.05
NT-4	52	3	37	41	196	748	0	43	53	403	0.04
TGF-β	52	98	1701	2064	11431	749	50	2129	2463	12750	0.05