. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Med Image Anal. 2013 Dec 18;18(6):914–926. doi: 10.1016/j.media.2013.12.005

Table 4.

SEM/confocal rigid registration errors on translation (t) and rotation (r)( $t = \sqrt{t_{x}^{2} + t_{y}^{2}}$ where t_x and t_y are translation errors in x and y directions respectively; t is in nm; pixel size is 40nm; r is in degree.) Here, the registration methods include: Original Image SSD and Original Image MI, registrations with original images based on SSD and MI metrics respectively; Standard IA SSD and Standard IA MI, registration with standard IA algorithm based on SSD and MI metrics respectively; Proposed IA SSD and Proposed IA MI, registration with our proposed IA algorithm based on SSD and MI metrics respectively.

	r_mean	r_median	r_std	t_mean	t_median	t_std
Proposed IA SSD	0.357	0.255	0.226	92.457	91.940	56.178
Proposed IA MI	0.239	0.227	0.077	83.299	81.526	54.310
Standard IA SSD	0.377	0.319	0.215	178.782	104.362	162.266
Standard IA MI	0.3396	0.332	0.133	140.401	82.667	135.065
Original Image SSD	0.635	0.571	0.215	170.484	110.317	117.371
Original Image MI	0.516	0.423	0.320	176.203	104.574	116.290