Table 1. Dynamics parameters in 1 SM, 8 SMs, adult stage of the SM lineage and following perturbations of cell differentiation.
The table summarizes the main dynamics parameters in control worms during development at larval stage L3 for the SM, L4 for the 8 SMs descendants and adult stage for the UMCs. Dynamics was also measured in adult worms after inhibition of differentiation by LIN-12Notch or HLH-8Twist depletion, as described in Figure 2. SEM = standard error of the mean; n = number of MTs tracked. n(worms per experiment) > 10.
| 1 SM (L3-stage) | 8 SMs (L4-stage) | UMCs (Adult) | lin-12(RNAi) | hlh-8(RNAi) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| mean | SEM | n | mean | SEM | n | mean | SEM | n | mean | SEM | n | mean | SEM | n | |
| Growth rate (μm/sec) | 0.13 | 0.004 | 79 | 0.15 | 0.005 | 356 | 0.17 | 0.004 | 275 | 0.13 | 0.003 | 274 | 0.19 | 0.005 | 221 |
| Shrinking rate (μm/sec) | 0.63 | 0.06 | 75 | 0.54 | 0.02 | 312 | 0.93 | 0.03 | 230 | 0.35 | 0.02 | 234 | 0.46 | 0.01 | 210 |
| Catastrophe (sec-1) | 0.17 | 0.01 | 79 | 0.13 | 0.003 | 356 | 0.06 | 0.003 | 275 | 0.19 | 0.01 | 274 | 0.14 | 0.003 | 221 |
| Rescue (sec-1) | 0.35 | 0.03 | 75 | 0.25 | 0.01 | 312 | 0.28 | 0.01 | 230 | 0.26 | 0.01 | 234 | 0.16 | 0.005 | 210 |