. 2014 Feb 19;31(7):1788–1800. doi: 10.1007/s11095-013-1283-1

Table I.

The Retention Time, MS Data and Characterization of Identified Phenolic Acids, Saponins and Tanshinones in Cardiotonic Pill

Peak no.	t_R (min)	[M-H]⁻(m/z)	Theoretical (m/z)	Error (ppm)	Formula	Identification
P1	8.85	197.0450	197.0455	−2.77	C₉H₁₀O₅	(s)-3-(3,4-dihydroxyphenyl) lactic acid
P2^a	9.76	197.0453	197.0455	−1.25	C₉H₁₀O₅	Tanshinol
P3^a	15.38	137.0246	137.0244	1.33	C₇H₆O₃	Protocatechuic aldehyde
P4^a	16.60	179.0351	179.0350	0.66	C₉H₈O₄	Caffeic acid
P5^a	20.70	537.1032	537.1038	1.12	C₂₇H₂₂O₁₂	Isolithospermic acid A
P6^a	21.89	537.1041	537.1038	−0.34	C₂₇H₂₂O₁₂	Isolithospermic acid B
P7^a	24.73	417.0830	417.0827	0.67	C₂₀H₁₈O₁₀	Salvianolic acid D
P8^a	29.40	339.0518	339.0510	2.28	C₁₈H₁₂O₇	Salvianolic acid G
P9^a	30.30	359.0780	359.0772	2.11	C₁₈H₁₆O₈	Rosmarinic acid
P10^a	30.67	537.1045	537.1038	1.58	C₂₇H₂₂O₁₂	Lithospermic acid
S1^a	31.04	977.5309	977.5327	1.62	C₄₇H₈₀O₁₈	Notoginsenoside-R1
S2^a	33.82	991.5497	991.5483	−1.47	C₄₈H₈₂O₁₈	Ginsenoside-Re
S3^a	34.15	845.4912	845.4904	−1.09	C₄₂H₇₂O₁₄	Ginsenoside-Rg1
P11^a	34.91	717.1461	717.1465	−0.55	C₃₆H₃₀O₁₆	Salvianolic acid B
P12^a	41.63	493.1146	493.1140	−1.21	C₂₆H₂₂O₁₀	Salvianolic acid A
P13^a	46.67	491.0990	491.0984	1.28	C₂₆H₂₀O₁₀	Salvianolic acid C
S4^a	50.10	845.4899	845.4904	−0.01	C₄₂H₇₂O₁₄	Ginsenoside-Rf
S5^a	52.13	1,153.6005	1,153.6011	1.04	C₅₄H₉₂O₂₃	Ginsenoside-Rb1
S6^a	52.76	815.4792	815.4798	1.12	C₄₁H₇₀O₁₃	Notoginsenoside-R2
S7^a	53.63	829.4951	829.4955	0.48	C₄₂H₇₂O₁₃	Ginsenoside-Rg2
S8	54.43	1,123.5878	1,123.5906	2.61	C₅₃H₉₀O₂₂	Ginsenoside-Rb3
S9^a	55.15	683.4379	683.4376	−0.56	C₃₆H₆₂O₉	Ginsenoside-Rh1
S10^a	55.56	1,123.5907	1,123.5906	−1.31	C₅₃H₉₀O₂₂	Ginsenoside-Rb2
S11^a	56.07	683.4370	683.4376	0.98	C₃₆H₆₂O₉	Ginsenoside-F1
S12^a	57.21	991.5507	991.5483	−2.39	C₄₈H₈₂O₁₈	Ginsenoside-Rd
S13^a	59.76	829.4959	829.4955	−0.20	C₄₂H₇₂O₁₃	Ginsenoside-F2
S14^a	60.45	829.4963	829.4955	−0.88	C₄₂H₇₂O₁₃	20(S)-Ginsenoside Rg3
S15^a	60.78	829.4936	829.4955	2.18	C₄₂H₇₂O₁₃	20(R)-Ginsenoside Rg3
T1^a	62.10	311.1288	311.1278	2.84	C₁₉H₁₈O₄	Tanshinone IIB
T2	63.61	337.1429	337.1434	1.70	C₂₁H₂₀O₄	Danshenxinkun D
T3^a	66.81	279.1021	279.1016	1.86	C₁₈H₁₄O₃	15,16-Dihydrotanshinone I
T4^a	71.01	277.0864	277.0859	2.96	C₁₈H₁₂O₃	Tanshinone I
T5^a	71.55	297.1496	297.1485	2.75	C₁₉H₂₀O₃	Cryptotanshinone
T6^a	72.92	279.1023	279.1016	−2.56	C₁₈H₁₄O₃	Methylenetanshinquinone
T7^a	74.48	295.1334	295.1329	1.77	C₁₉H₁₈O₃	Tanshinone IIA
T8^a	75.01	283.1704	283.1693	−4.07	C₁₉H₂₂O₂	Miltirone

P1–P13 phenolic acids; S1–S15 saponins; T1–T8 tanshinones. t_R: retention time

^aCompared with reference compounds