Fig. 2.

Effect of platelet-activating factor (PAF) and cyclooxygenase inhibitors on Ca²⁺-induced PS exposure in RBCs from SCD patients. RBCs were incubated in HK saline in the presence or absence of inhibitor for 30 min prior to treatment with ionophore for 30 min (as in Fig. 1b). a Effect of treatment with the PAF inhibitor ABT491 (1–50 μM). b Effect of treatment with the cyclooxygenase inhibitor acetylsalicylic acid (50–200 μM). Symbols represent means ± SEM, n = 3, except for 5 μM ABT491, where n = 2. There was no significant difference between values in the presence or absence (controls) of the inhibitors