Fig. 5.

Effect of platelet-activating factor (PAF) and phospholipase A2 (PLA2) inhibitors on Ca²⁺-induced PS exposure in RBCs from SCD patients. RBCs were incubated in HK saline, LK saline or LK saline plus inhibitor for 30 min before treatment with ionophore for 30 min (as in Fig. 1b). a Effect of the PAF inhibitor ABT491 (50 μM). Histograms represent means ± SEM, n = 7. ^# p < 0.05, *p < 0.005. b Effect of the PLA2 inhibitor quinacrine (100 μM). Histograms represent means ± SEM, n = 3. *p < 0.03