Fig. 4.

Mesenteric small arteries in vivo respond to exogenous NA with changes in arterial inner diameter: matched eGFP-siRNA and Tmem16a-siRNA-transfected arteries from the same rat were compared. a Averaged inner diameters of arteries transfected with eGFP-siRNA and Tmem16a-siRNA and their changes in response to NA. n = 7, *P < 0.05. Representative curves showing the inner diameter changes in response to NA of eGFP-siRNA-transfected artery (b) and Tmem16a-siRNA-transfected artery in vivo (c). d The distribution of vasomotion amplitudes over oscillation frequencies 0–0.5 Hz for eGFP-siRNA-transfected arteries (n = 7) and Tmem16a-siRNA-transfected arteries in vivo (two out of seven arteries did not oscillate and were therefore not included in the analysis; n = 5). *P < 0.05