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. Author manuscript; available in PMC: 2014 Jun 19.
Published in final edited form as: Am J Cardiol. 2011 Sep 29;109(1):95–99. doi: 10.1016/j.amjcard.2011.08.010

Table 2. High-sensitivity C-reactive protein tertiles and mortality.

Relative Hazard (95% conficence interval) for death in Atherosclerosis Risk in Communities (ARIC) participants with prevalent atrial fibrillation by high-sensitivity C-reactive protein tertiles.

Variable Tertiles of high-sensitivity C-reactive protein (mg/L) p for trend
<2.00 (n=96) 2.00–5.99 (n=96) ≥6.00 (n=101)
Deaths 30 (31%) 42 (44%) 62 (61%) -
Relative Hazard for death Model 1 1 [Reference] 1.33 (0.83–2.13) 2.13 (1.36–3.33) p<0.0001
Model 2 1 [Reference] 1.26 (0.77–2.06) 2.04 (1.24–3.36) p<0.0001
Model 3 1 [Reference] 1.24 (0.75–2.03) 2.52 (1.49–4.25) p<0.0001

Model 1: Cox proportional hazards model adjusted for CHADS2 score.

Model 2: Cox proportional hazards model adjusted for CHADS2 score, sex, race, center, smoking, prevalent coronary heart disease, body mass index, education, antiplatelet medication, anticoagulant medication, statins, ECG-based left ventricular hypertrophy.

Model 3: Cox proportional hazards model adjusted for age, sex, prevalent heart failure, diabetes, sistolic blood pressure, antihypertensive medications, prevalent stroke, race, center, smoking, prevalent coronary heart disease, body mass index, education, antiplatelet medication, anticoagulant medication, statins, ECG-based left ventricular hypertrophy.