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. 2014 Jun 19;5:294. doi: 10.3389/fimmu.2014.00294

Figure 3.

Figure 3

Characterization of memory T (TM) cells in gastric LPMC and PBMC from children, adults, and the elderly. (A) Representative scatter plots of the gating strategy used to characterize T cell subsets in LPMC and PBMC: naïve (CD62L+CD45RA+), central memory (TCM, CD62L+CD45RA−), effector memory (TEM, CD62L−CD45RA−), and effector memory expressing CD45RA (TEMRA, CD62L−CD45RA+). Data shown are from a 12 year-old child. (B) Cumulative data showing the median % and range of CD3, CD4, CD8, TEM populations in gastric LPMC and PBMC from all three age groups. (C) Identification of tissue-resident memory T (TRM) cells in gastric LPMC. Representative plots showing expression of TRM cells as defined by the concomitant expression of CD103 and CD69 markers on CD8+ and CD4+ T cells in gastric LPMC and PBMC. (D) Cumulative data (n = 10) showing the percentage of gastric TRM cells among CD8+ and CD4+ T cells from LPMC and PBMC (***p < 0.0005).