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. 2014 Jun 19;5:294. doi: 10.3389/fimmu.2014.00294

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Copyright © 2014 Booth, Toapanta, Salerno-Goncalves, Patil, Kader, Safta, Czinn, Greenwald and Sztein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of integrin α4β7 expression on memory T (T_RM and T_EM) cells in gastric LPMC and PBMC. (A) Representative scatter plots showing integrin α4β7 expression on CD8⁺ and CD4⁺ gastric LPMC and PBMC (data shown are from a 12-year-old child). (B) Cumulative data (n = 14) showing the percentage of CD8⁺ and CD4⁺ T_RM (LPMC) as well as CD8⁺ and CD4⁺ T_EM (PBMC) cells expressing integrin α4β7. Significant differences are denoted as follows: **p < 0.005; ***p < 0.0005. (C) Cumulative data comparing the percentage of CD8⁺ or CD4⁺ T_RM subsets (LPMC) expressing integrin α4β7 by age group. Closed and open symbols represent CD8⁺ and CD4⁺ T_RM cells, respectively: adults (Ad); children (Ch); elderly (El).