Table 1.

Comparison between ESC and iPSC.

	iPS	ES cells
Reported in humans	Yes	Yes
Embryos or donor oocytes required	No	Yes
Stemness marker expressed	Yes	Yes
Teratomas produced	Yes	Yes
Utility as a research tool	Allows repeated development	Allows the study of development
Can be used as models for human diseases	Yes	Some
Can be used in a screen to identify drugs	Yes	Yes
Variable fates	Likely	Yes
Develop into specific human tissues	To be shown	Yes
Genetically match the patient	Unknown	No
Additional information	Cells are genetically modified in current methods	Cells are allogeneic and might cause immune rejection

Adapted from Nishikawa et al. (34). With permission from Macmillan Publishers Ltd.