Table 3.
Clinicopathological features of patients with PROM1 and CRTC2 mutations
| Patient | Gender | Age (yrs.) | Type | T | N | M | Stage | Differentiation | Tumor size (cm) | Family history | Smoking status | Pack years |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PROM1 | ||||||||||||
| LCa-15 |
M |
58 |
ADC |
1a |
0 |
0 |
IA |
Poor |
1.2 × 1 × 0.8 |
No |
Never |
|
| LC-116 |
M |
70 |
SCC |
4 |
0 |
0 |
IIIA |
Poor-moderate |
13.5 × 12 × 6 |
Yes |
Current |
182 |
| LC-122 |
F |
59 |
ADC |
2a |
1 |
1b |
IV |
Poor |
4.3 × 2.3 × 3 |
No |
Never |
|
| LC-215 |
M |
68 |
SCC |
2b |
1 |
0 |
IIB |
Poor |
6.1 × 4.9 × 5 |
No |
Current |
546 |
| LC-275 |
F |
54 |
ADC |
4 |
2 |
1a |
IV |
Poor |
17 × 11 × 4.1 |
No |
Never |
|
| LCTb-17 |
M |
58 |
ADC |
2a |
1 |
0 |
IIA |
Moderate |
4 × 3.5 × 3.5 |
No |
Current |
182 |
| LCT-51 |
M |
61 |
SCC |
1a |
0 |
0 |
IA |
Poor |
2 × 1.5 × 1.4 |
No |
Current |
364 |
| LCT-181 |
F |
56 |
ADC |
2a |
1 |
0 |
IIA |
Moderate-well |
4 × 3 × 3 |
No |
Never |
|
|
CRTC2 | ||||||||||||
| LC-207 |
M |
72 |
ADC |
2a |
0 |
0 |
IB |
Moderate |
2.3 × 3.4 × 2 |
No |
Current |
365 |
| LC-250 |
F |
65 |
ADC |
2a |
1 |
0 |
IIA |
Poor-moderate |
4 × 4 × 3.5 |
No |
Never |
|
| LCT-81 |
F |
57 |
ADC |
2a |
0 |
0 |
IB |
Poor-moderate |
3 × 2.5 × 2.5 |
No |
Never |
|
| LCT-94 |
M |
69 |
SCC |
1b |
0 |
0 |
IA |
Poor |
2.5 × 1.5 × 1.0 |
No |
Current |
500 |
| LCT-111 |
M |
52 |
SCC |
2a |
1 |
0 |
IIA |
Poor-moderate |
4 × 3.5 × 2.5 |
No |
Current |
280 |
| LCT-160 |
M |
41 |
ADC |
2a |
1 |
0 |
IIA |
Moderate |
4 × 3.5 × 4 |
Yes |
Never |
|
| LCT-171 | F | 69 | ADC | 2a | 0 | 0 | IB | Poor-moderate | 4 × 4 × 3 | No | Never | |
ablood sample of lung cancer; btissue sample of lung cancer and matched normal lung tissue.
ADC, adenocarcinoma; SCC, squamous cell carcinoma.