Table 2.

Absolute risk for congenital cardiac malformations in women with and without antidepressant exposure by class; overall cohort. Medicaid Analytic eXtract, 2000–2007.

Exposure groups	Total	Any cardiac malformation		RVOTO		VSD		Other cardiac malformation
		Events	Risk (/10,000)	Events	Risk (/10,000)	Events	Risk (/10,000)	Events	Risk (/10,000)
Unexposed	885,115	6,403	72.3	1,045	11.8	3,212	36.3	3,232	36.5
All antidepressants	64,389	580	90.1	84	13.1	286	44.4	318	49.4
SSRI	46,144	416	90.2	61	13.2	201	43.6	226	49.0
Paroxetine	11,126	93	83.6	16	14.4	44	39.6	48	43.1
Sertraline	14,040	129	91.9	17	12.1	63	44.9	71	50.6
Fluoxetine	11,048	99	89.6	16	14.5	48	43.5	55	49.8
TCA	5,954	42	70.5	8	13.4	24	40.3	18	30.2
SNRI	6,904	75	108.6	12	17.4	39	56.5	38	55.0
Other	7,055	74	104.9	8	11.3	31	43.9	46	65.2
Bupropion	8,856	76	85.8	11	12.4	39	44.0	49	55.3