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. Author manuscript; available in PMC: 2014 Jun 19.
Published in final edited form as: Handb Exp Pharmacol. 2011;(204):193–210. doi: 10.1007/978-3-642-17969-3_8

Fig. 2.

Fig. 2

Epac mediates some of the effects of cAMP on endothelial permeability. HUVEC were stimulated with thrombin, thrombin + 10 μM forskolin, or thrombin + 100 μM 8-CPT-2′OMe-cAMP, and permeability assays were performed as described previously (Surapisitchat et al. 2007). Data represent mean (mean±SEM) from two independent experiments using HUVEC isolated from two different umbilical cords