Table 2.
Wet-to-dry-weight ratio, histological and immunohistochemical analyses
Variable | control | rhATIII | sham |
---|---|---|---|
Wet-to-dry-weight ratio | 6.0 ± 0.3# | 4.7 ± 0.3† | 4.5 ± 0.1 |
Obstruction bronchi (score) | 13.7 ± 1.9# | 4.8 ± 0.7† | 3.2 ± 1.2 |
Obstruction bronchioli (score) | 3.5 ± 0.8# | 0.8 ± 0.2† | 0.9 ± 0.1 |
Alveolar edema (score) | 1.1 ± 0.3# | 0.3 ± 0.2† | 0.0 ± 0.0 |
Pulmonary hemorrhage (score) | 0.25 ± 0.09# | 0.04 ± 0.04 | 0.0 ± 0.0 |
Myeloperoxidase activity (U·mL−1) | 12.2 ± 1.5# | 8.4 ± 0.4#† | 4.0 ± 0.7 |
, p< .05 vs. sham;
, p< .05 vs. control; each group n = 6
rhATIII, recombinant human antithrombin III; w/d-weight, wet-to-dry-weight ratio