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. 2013 May 7;31(8):1511–1522. doi: 10.1002/stem.1426

Figure 5.

Figure 5

Hes1 homozygous null embryonic stem (ES) cells differentiate more rapidly into both neural and non-neural lineages. (A–D): Quantitative polymerase chain reaction analysis of control wild-type ES cells, Hes1 homozygous null ES cells, or Hes1 homozygous null cells rescued with a constitutively expressed Hes1 transgene, undergoing neural differentiation in serum-free monolayer (A, C) or undergoing non-neural differentiation in serum without LIF (B, D). All data are represented as mean ± SD. *Indicates p < .1 relative to wild-type control cells.