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. Author manuscript; available in PMC: 2015 Apr 18.
Published in final edited form as: ACS Chem Biol. 2014 Feb 10;9(4):957–966. doi: 10.1021/cb400898t

Figure 4. AFM images of proMMP-7-E195A mixtures with heparin (A) and heparan sulfate (B) suggest similarities in the heterogeneous tandem assemblies.

Figure 4

300×500 nm images are plotted for mixtures of (A) 100 nM proMMP-7-E195A with 2.5 µg/ml bovine lung heparin or (B) 50 nM proMMP7-E195A with 2.5 ug/ml bovine heparan sulfate. Note that bovine heparin and HS are polydisperse, with chain lengths from 5 to 50 kDa. The vertical scale spans 0 to 4 nm for both panels.