Fig. 2.
Upper panels: outflow indicator-diultion curves fore iododdesmethylimipramine (IDMI), sucrose (extracellular marker), and albumin (intravascular marker) from a Krebs-Ringer bicarbonate buffer-perfused isolated rabbit heart at two flows. Time scales are logarithmic (last point is at 7 min). Logarithmic ordinate covers four orders of magnitude. Lower panels: high instantaneous extractions for IDMI [E(t)] indicate rapid exit from vascular space. High IDMI net extraction [Enet (t)] values indicate long retention.