Table 3. rBGM Reductions at the Peak Level in the Lithium Group in Comparison to the Placebo Groupa.
pFWEb | pFDRb | Z score | peak voxel (Talairach) | |
---|---|---|---|---|
left cerebellum, posterior lobe, inferior semi-lunar lobule | 0.007 | 0.055 | 4.48 | –30, −64, −39 |
left cerebellum, posterior lobe, cerebellar tonsil | 0.013 | 0.055 | 4.31 | –30, −52, −33 |
left cerebellum, anterior lobe, culmen | 0.013 | 0.055 | 4.30 | –28, −48, −26 |
left cerebellum, anterior lobe, culmen | 0.016 | 0.061 | 4.24 | –22, −60, −26 |
left cerebellum, posterior lobe, cerebellar tonsil | 0.031 | 0.088 | 4.04 | –18, −44, −33 |
right cerebellum, posterior lobe, cerebellar tonsil | 0.009 | 0.122 | 4.42 | 18, −46, −35 |
right cerebellum, posterior lobe, cerebellar tonsil | 0.013 | 0.122 | 4.31 | 25, −54, −39 |
right cerebellum, posterior lobe, pyramis | 0.033 | 0.152 | 4.04 | 28, −68, −30 |
right cerebellum, anterior lobe, culmen | 0.043 | 0.163 | 3.95 | 38, −48, −30 |
Small volume correction analysis directed to cerebellum as area of interest (maps generated for analysis with a minimum threshold of p < 0.001, uncorrected for multiple comparisons).
Nonpaired t test; differences in rBGM (p values) were considered as significant only after correction for multiple comparisons (FWE, familywise error; FDR, false discovery rate).